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目的:研究急性心肌梗塞(AMI)合并糖尿病与细胞因子的关系。方法:将AMI合并糖尿病与非糖尿病AMI各80例分为临床组与对照组进行TNF-α与IL-1β的测定。结果:⒈临床组TNF-α、IL-1β明显高于对照组,p<0.001,有显著性差异;⒉临床组冠脉多支病变77.5%明显高于对照组52.5%,p<0.001,有显著性差异。结论:AMI合并糖尿病TNF-α、IL-1β明显升高,冠脉病变更重。
Objective: To study the relationship between acute myocardial infarction (AMI) and diabetes mellitus and cytokines. Methods: Eighty AMI patients with AMI and non-diabetic AMI were divided into clinical group and control group for determination of TNF-α and IL-1β. Results: (1) The levels of TNF-α and IL-1β in the clinical group were significantly higher than those in the control group (p <0.001), and there was a significant difference between the two groups. (2) The multi-vessel disease in the clinical group was significantly higher than that in the control group (77.5% vs 52.5%, p < Significant difference. Conclusion: The levels of TNF-α and IL-1β in patients with AMI complicated with diabetes mellitus were significantly increased and the coronary lesions were more serious.