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目的:探讨阿托伐他汀联合厄贝沙坦治疗原发性高血压的临床效果。方法:本研究按照随机数字表法将96例原发性高血压患者随机分为研究组和对照组,研究组采用阿托伐他汀联合厄贝沙坦治疗,对照组单独采用厄贝沙坦治疗,对两组患者的临床疗效,并进行对比研究。结果:研究组的显效率和总有效率均明显高于对照组,且差异具有统计学意义(P均<0.05)。两组治疗前后的LVMI比较均有明显差异,且差异具有统计学意义(P均<0.05)。两组不良反应发生率无明显差异(P>0.05)。结论:厄贝沙坦联合苯磺酸氨氯地平治疗原发性高血压的疗效显著,不良反应少,值得临床推广使用。
Objective: To investigate the clinical effect of atorvastatin combined with irbesartan in the treatment of essential hypertension. Methods: According to the random number table method, 96 patients with essential hypertension were randomly divided into study group and control group, the study group was treated with atorvastatin combined with irbesartan, the control group treated with irbesartan alone , The clinical efficacy of two groups of patients, and comparative study. Results: The effective rate and total effective rate of the study group were significantly higher than that of the control group, and the difference was statistically significant (all P <0.05). LVMI before and after treatment in both groups were significantly different, and the difference was statistically significant (P all <0.05). No significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: The effect of irbesartan combined with amlodipine besylate in the treatment of essential hypertension is significant, with fewer adverse reactions, which is worthy of clinical application.