论文部分内容阅读
鉴于日本农业用肥以化肥取代了人粪,公众健康和环境卫生的改善及经济增长使大多数人过着都市化的生活方式,二次大战后20年间流行的蠕虫病发生率已显著降低。但是,国际交往的增加造成了寄生虫病输入的问题,因此有必要寻求有效的抗寄生虫药物.尽管近来许多抗寄生虫药物已在世界上广泛应用,但因申请注册需要费用,商业效益差,一旦出现严重副反应要受到法律追究等缘故,许多制药公司不愿意在日本注册。为了收集未在日本注册抗寄生虫药物的临床资
Given that Japanese agricultural fertilizers have replaced human waste with chemical fertilizers, improvements in public health and sanitation and economic growth have led most people to an urbanized lifestyle and the prevalence of helminthiasis has drastically decreased over the two decades after World War II. However, the increase of international communication has caused the problem of parasitic diseases input, therefore, it is necessary to find effective anti-parasitic drugs.Although many anti-parasitic drugs have been widely used in the world recently, the cost of applying for registration is low and the commercial benefit is poor , In the event of serious side effects to be investigated by law and other reasons, many pharmaceutical companies do not want to register in Japan. In order to collect clinical data on antiparasitic drugs not registered in Japan