颗粒状角膜营养不良(granular corneal dystro-phy,GCD)是角膜营养不良之一,属于常染色体显性遗传病,是一种少见疾病。临床工作中发现颗粒状角膜营养不良一家系,4代22人中已发现10人患病,随着第4代人口的出生,患病人数将继续增加。现报告如下。1临床资料先证者,男,20岁,学生。 Granular corneal dystrophy (granular corneal dystro-phy, GCD) is one of corneal dystrophy, is an autosomal dominant disease, is a rare disease. In clinical work, there were 10 pediatric corneal dystrophy families found in 4 generations and 10 cases were found to be diseased. As the fourth generation of the population is born, the number of patients with the corneal dystrophy will continue to increase. The report is as follows. 1 clinical data proband, male, 20 years old, student.