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为减轻绝经后潮热,已采用一些治疗方法,包括旨在减轻紧张心理与症状的治疗,以及针对纠正雌激素缺乏的内分泌治疗.雌激素药物治疗已普遍得到成功.然而,鉴于在一些病人中雌激素治疗的不良副作用和不能耐受,目前正研究孕激素类药物在减轻子宫及卵巢切除术后妇女的潮热所起的作用.作者在两年中为68例绝经前病人进行了子宫和双侧卵巢切除术,术后嘱病人在每天发生潮热3次以上时到妇科门诊.治疗前,记录潮热发生的频率和程度,并进行乳房和盆器检查.采用双盲法选用孕激素类药物,从开始治疗日的第二、三、六月记录治疗反应.除6人失访外,余62例中40例肌注甲孕酮150mg(Ⅰ组); 22名妇女给17-羟孕酮己酸盐
In order to reduce post-menopausal hot flashes, several treatments have been adopted, including those aimed at alleviating stress and symptoms, and endocrine therapies aimed at correcting estrogen deficiency.Health management has generally been successful.However, in some patients, The adverse side effects and intolerance of estrogen therapy are currently studying the role of progestin-type drugs in reducing the hot flashes in women after uterine and ovariectomized researches. The authors studied 68 premenopausal patients over two years in the uterus and Bilateral ovariectomy, postoperative instruct patients in hot flashes more than 3 times a day to the gynecological clinic before treatment, record the frequency and extent of hot flashes, and breast and pelvic examination using double-blind selection of progesterone In the second, third, and sixth month, the treatment response was recorded.Among the 6 patients lost to follow-up, 40 cases were given intramuscular megesterone 150 mg (group I) in 62 cases and 22 women were given 17-hydroxy Progesterone hexanoate