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目的探讨控制性超促排卵过程中人绒毛膜促性腺激素(hCG)日血清雌二醇水平及其对促排卵结局和妊娠的影响。方法回顾性分析因输卵管阻塞和/或男方少、弱精在我院生殖中心进行IVF/ICSI-ET助孕的患者的资料,比较不同E2水平患者的获卵数、受精率等促排卵相关参数及临床妊娠率。结果 HCG日E2水平>5000pg/ml组患者的获卵数明显高于HCG日E2水平较低的两组,但是HCG日E2水平<3500pg/ml组患者的受精率及临床妊娠率高于E2水平较高的患者,差异有统计学意义。结论控制性超促排卵过程中HCG日E2水平对促排卵结局有影响,HCG日E2水平过高会影响促排卵患者的临床妊娠率。
Objective To investigate the serum estradiol level of human chorionic gonadotropin (hCG) and its effect on ovulation induction outcome and pregnancy during controlled ovarian hyperstimulation. Methods A retrospective analysis was made on the data of ovulation obstruction and / or the number of men and women with weakness and weakness in IVF / ICSI-ET assisted pregnancy in our reproductive center. The ovulation-related parameters And clinical pregnancy rate. Results The number of oocytes retrieved from patients with E2 level> 5000 pg / ml on HCG day was significantly higher than those with lower E2 level on HCG day. However, the fertilization rate and clinical pregnancy rate of patients with E2 level <3500 pg / ml on HCG day were higher than that of E2 The higher the patient, the difference was statistically significant. Conclusion The level of E2 on the day of HCG during the controlled ovarian hyperstimulation has an effect on the outcome of ovulation. The high E2 level on the HCG day will affect the clinical pregnancy rate of patients with ovulation induction.