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目的探讨CT冠状动脉造影不同对比剂用量对冠状动脉及冠状静脉窦强化程度的影响。方法选择2013-12/2014-12月来作者医院进行治疗的124例冠心病患者,按照随机数字表法分为高剂量组和低剂量组,各62人。比较两组患者冠状动脉成像参数;记录两组患者冠状静脉窦、升主动脉、降主动脉、左冠状动脉主干和右冠状动脉近段的CT值。结果低剂量组患者对比剂用量显著低于高剂量组患者(P<0.05);两组患者在其他冠状动脉成像参数上差异无统计学意义(P>0.05);两组患者CT冠状动脉造影中升主动脉、降主动脉、左冠状动脉主干和右冠状动脉近段的强化强度之间差异无统计学意义(P>0.05),但低剂量组患者冠状静脉窦的强化程度显著低于高剂量组患者(P<0.05)。结论采用640层动态容积CT对冠状动脉进行造影时,采用0.7 ml/kg的对比剂剂量能达到较好的冠状动脉强化效果,同时有效避免冠状静脉窦的强化,值得临床推广。
Objective To investigate the effects of different contrast agents on the degree of coronary artery and coronary sinus sinus enhancement by CT coronary angiography. Methods A total of 124 patients with coronary heart disease who were admitted to the author’s hospital from January 2013 to December 2014 and December were divided into high dose group and low dose group according to the random number table. Coronary artery imaging parameters were compared between the two groups. CT values of coronary sinus, ascending aorta, descending aorta, left main coronary artery, and proximal right coronary artery were recorded. Results The dosage of contrast agent in low-dose group was significantly lower than that in high-dose group (P <0.05). There was no significant difference in the parameters of other coronary arteries between the two groups (P> 0.05) There was no significant difference in enhancement intensities between ascending aorta, descending aorta, left main coronary artery and proximal right coronary artery (P> 0.05), but the degree of enhancement of coronary sinus in patients in low dose group was significantly lower than that in high dose Group patients (P <0.05). Conclusions When coronary angiography is performed with 640-slice dynamic volumetric CT, the contrast-enhanced dose of 0.7 ml / kg can achieve better coronary artery enhancement and effectively avoid the enhancement of coronary sinus, which is worthy of clinical promotion.