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目的 为降低抗结核药物肝损害 ,观察螺旋藻预防肝脏损害的作用。方法 螺旋藻与抗结核药物联合应用 ,螺旋藻胶囊 3粒口服 ,每日 3次 ,服用 6个月。结果 螺旋藻治疗组 6个月末肝损害发生率为 2 .4 % ,对照组为 15.5% ,两组比较差异有显著性 (P <0 .0 1)。螺旋藻无毒副作用。结论螺旋藻与抗结核药物联用可显著降低抗结核药物肝损害的发生率 ,值得临床进一步研究。
Objective To reduce the anti-TB drug liver damage, observe the role of Spirulina in preventing liver damage. Methods Spirulina combined with anti-TB drugs, spirulina capsule 3 orally, 3 times a day, taking 6 months. Results The incidence of liver damage at the end of 6 months in Spirulina treatment group was 2.4% and that in the control group was 15.5%. There was significant difference between the two groups (P <0.01). Spirulina non-toxic side effects. Conclusion Spirulina combined with anti-TB drugs can significantly reduce the incidence of anti-TB drug liver damage, worth further clinical study.