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目的:探讨女性迟发性痤疮的有效治疗方法及机理。方法:将60例患者随机分为治疗组40例,对照组20例。治疗组采用刺络拔罐联合红蓝光治疗,对照组采用口服丹参酮胶囊和外用玫芦消痤膏治疗,观察疗程为8周。评价其临床疗效并观察2组患者治疗前后外周血中睾酮(T)、雌二醇(E2)。结果:临床疗效总有效率治疗组为92.5%,对照组为90.0%,2组比较,差异无显著性意义(P>0.05)。治疗后治疗组血清T水平下降,差异有非常显著性意义(P<0.01),E2水平上升,差异无显著性意义(P>0.05);对照组血清T、E2水平变化不明显,治疗前后比较,差异均无显著性意义(P>0.05)。结论:刺络拔罐联合红蓝光治疗女性迟发性痤疮具有明显的临床疗效,其可能通过调节机体性激素水平达到治疗目的。
Objective: To explore the effective treatment of delayed acne in women and its mechanism. Methods: Sixty patients were randomly divided into treatment group (40 cases) and control group (20 cases). The treatment group was treated by puncturing and cupping combined with red and blue light. The control group was treated with oral tanshinone capsule and external ruby acne cream. The course of treatment was 8 weeks. The clinical efficacy was evaluated and the levels of testosterone (T) and estradiol (E2) in peripheral blood were observed before and after treatment in two groups. Results: The total effective rate of the treatment group was 92.5% in the control group and 90.0% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, serum T level decreased, the difference was significant (P <0.01), E2 level increased, the difference was not statistically significant (P> 0.05); control group serum T, E2 levels did not change significantly before and after treatment , There was no significant difference (P> 0.05). Conclusion: Pricking cupping combined with red and blue light treatment of women with delayed acne has obvious clinical efficacy, which may be through the regulation of sex hormone levels for therapeutic purposes.