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新药Fenoprofen(苯氧布洛芬),又名Fenopron,属dL-2(3-phehoxyphenyl)苯氧苯丙酸盐,1976年用于治疗类风湿性关节炎。本院自1984年10月至11月用苯氧布洛芬治疗类风湿性关节炎(RA)15例,兹将初步结果报道如下: 15例病人皆符合美国风湿病学会(ARA)制订的诊断标准,男1例,女14例;年龄22~53岁;病程半年~30年,平均8年;活动性RA有14例。按ARA分期,关节X光相属1期者5例、2期4例、3期6例。关节功能为1级者3例、2级9例、3级3例。5例有关节外表现如肾受累等。治疗前仅1例应用糖皮质激素,余14例应用了
Fenoprofen (phenoxybuprofen), also known as Fenopron, is a dL-2 (3-phehoxyphenyl) phenyipropionate, used in 1976 to treat rheumatoid arthritis. 15 cases of rheumatoid arthritis (RA) were treated with phenoxybuprofen in our hospital from October to November, 1984 and the preliminary results were reported as follows: All 15 patients were diagnosed according to the American College of Rheumatology (ARA) Standard, 1 males and 14 females; aged 22 to 53 years; duration of six months to 30 years, an average of 8 years; active RA in 14 cases. According to ARA stage, joint X-ray belongs to phase 1 in 5 cases, stage 2 in 4 cases and stage 3 in 6 cases. The joint function was grade 1 in 3 cases, grade 2 in 9 cases, and grade 3 in 3 cases. 5 cases of extra-articular manifestations such as kidney involvement. Only 1 case before treatment with glucocorticoid, more than 14 cases applied