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[目的]观察化痰通腑汤联合西药治疗中风急性期疗效。[方法]使用随机平行对照方法,将70例住院患者按抛硬币法简单随机分为两组。对照组35例吸氧、抗感染、脱水降颅压、调控血压、营养脑细胞、营养支持及维持水电解质平衡。治疗组35例化痰通腑汤(胆南星10g,芒硝冲服6g~9g,生大黄后下10g,全瓜萎30g;头痛、项强及水肿加泽兰、川牛膝、益母草各15g;神志不清加安宫牛黄丸;热象明显加栀子12g,牡丹皮10g,黄芩12g;年老体弱津亏加生地黄、麦冬各15g;瘀血严重加桃仁10g,丹参15g,川芎10g;肝阳上亢加生龙骨30g,石决明12g,钩藤30g;语言不利加全蝎6g,石菖蒲12g;大便通畅后去芒硝;大便通畅减生大黄),1剂/d,水煎200m L,早晚分服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、神经功能缺损评分、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈14例,显效15例,有效4例,无效2例,总有效率94.29%。对照组痊愈6例,显效7例,有效14例,无效8例,总有效率77.14%。治疗组疗效优于对照组(P<0.05)。[结论]化痰通腑汤联合西药治疗中风急性期疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Huatan Tongfu Decoction combined with western medicine in acute stage of stroke. [Methods] Using randomized parallel control method, 70 inpatients were randomly divided into two groups according to the coin-tossing method. The control group of 35 patients with oxygen, anti-infection, dehydration decreased intracranial pressure, blood pressure regulation, nutrition brain cells, nutritional support and maintain water and electrolyte balance. The treatment group of 35 cases of phlegm Tongfu Decoction (bile Southern Star 10g, mirabilite flush 6g ~ 9g, raw rhubarb 10g, full melon wilt 30g; headache, Xiangqiang and edema plus Zeeland, Achyranthes, Motherwort 15g; Unclear plus Angong Niuhuang Wan; heat significantly increased Gardenia 12g, moutan 10g, Scutellaria 12g; aged frail Tianjin loss plus Rehmannia, Ophiopogon japonicus 15g; stasis with serious peach 10g, Salvia 15g, Chuanxiong 10g ; Liver hyperactivity plus keel 30g, stone Cassia 12g, Uncaria 30g; language disadvantage plus Scorpio 6g, Shichangpu 12g; stool patency to Glauber’s salt; defecation patency rhubarb), 1 / d, decoction 200m L , Morning and evening sub-service; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observation of clinical symptoms, neurological deficit score, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group cured 14 cases, markedly effective in 15 cases, effective in 4 cases, ineffective in 2 cases, the total effective rate was 94.29%. The control group cured 6 cases, markedly effective in 7 cases, effective in 14 cases, ineffective in 8 cases, the total effective rate was 77.14%. The treatment group was better than the control group (P <0.05). [Conclusion] Huatan Tongfu Decoction combined with Western medicine in the treatment of acute stroke has satisfactory curative effect without serious adverse reactions and is worth popularizing.