多发性骨髓瘤是一种浆细胞恶性增生的疾病。临床上引起骨痛、病理性骨折、贫血、肾功能损害、反复感染等一系列多系统、多样化表现。近年来,越来越多的患者起病较为隐匿,临床仅表现为腰酸、乏力或尿路刺激症状,而就诊于肾内科。我科于1998-05～1999-10,收治20例多发性骨髓瘤患? Multiple myeloma is a disease of malignant proliferation of plasma cells. Clinically caused by bone pain, pathological fractures, anemia, renal damage, repeated infections and a series of multi-system, diverse performance. In recent years, more and more patients have become more insidious and have only clinical symptoms of backache, fatigue, or urinary tract irritation, and they are present in the Department of Nephrology. In our department from 1998-05 to 1999-10, 20 patients with multiple myeloma were treated.