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多发性硬化急性加重是指由扩大的能力丧失状况评分(EDSS)测定的原有症状的显著加重或新发现的神经系统缺损至少24小时。新的炎性损害可以没有相一致的症状,因此对疾病活动进行评价需要一些客观指标。本文对血浆S-100蛋白浓度增加是否可以作为多发性硬化急性加重的标志进行了探讨。
Acute exacerbation of multiple sclerosis means a significant exacerbation of the original symptoms as measured by the Extended Disability Status Score (EDSS) or a newly discovered neurological deficit for at least 24 hours. New inflammatory lesions do not have consistent symptoms, so evaluating disease activity requires some objective measures. In this paper, whether increased plasma S-100 protein concentration can serve as a marker of acute multiple sclerosis was explored.