论文部分内容阅读
近年来研究发现 ,胃泌素 (GAS)和五肽GAS能保护大鼠胃黏膜 ,促进胃黏膜损伤的愈合[1] ,但其作用机制尚不清楚。前列腺素 (PGs)在维持胃肠黏膜的完整性和黏膜损伤后的修复中发挥重要作用 ,环氧合酶 (COX)是合成PGs的限速酶 ,已知COX至少有两种亚型 ,即COX 1和COX 2。本研究应用W
Recent studies have found that gastrin (GAS) and penta-peptide GAS can protect the gastric mucosa of rats and promote the healing of gastric mucosal injury [1], but the mechanism of action is still unclear. Prostaglandins (PGs) play an important role in maintaining the integrity of gastrointestinal mucosa and repair of mucosal injury. Cyclooxygenase (COX) is a rate-limiting enzyme in the synthesis of PGs. There are at least two subtypes of COX, namely COX 1 and COX 2. This study applies W