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目的：探讨流行性乙型脑炎（简称乙脑）、化脓性脑膜炎（简称化脑）、结核性脑膜炎（简称结脑）、正常脑脊液（CSF）中免疫球蛋白（Ig）、C-反应蛋白（CRP）与临床的关系。方法：对83例乙脑、25例化脑、28例结脑、18例正常脑脊液中免疫球蛋白、C-反应蛋白采用杨顺江法与微量免疫荧光（MIF）法进行了分析测定。结果：发现18例正常组脑脊液，血中CRP全为阴性。83例乙脑脑脊液中Ig重型、极重型明显低于轻型、普通型。化脑脑脊液中IgM显著增高，结脑IgG升高明显。极重型乙脑血和脑脊液中CRP均明显升高。而轻型病例脑脊液中无1例阳性。结论：证实测定脑脊中的Ig和CRP对中枢神经系统感染或作为感染性疾病的诊断、鉴别诊断有很大的帮助，特别是对鉴别乙脑、化脑、结脑有一定的参考价值。对乙脑的分型及各型乙脑转归的判断有一定的帮助。
Objective: To investigate the clinical significance of epidemic encephalitis (JE), purulent meningitis, tuberculous meningitis, immunoglobulin (Ig) in normal cerebrospinal fluid (CSF) Relationship between reactive protein (CRP) and clinical. Methods: Immunoglobulin was detected in 83 cases of JE, 25 cases of brain, 28 cases of tuberculous brain and 18 cases of normal cerebrospinal fluid. C-reactive protein was analyzed by Yang Shunjiang method and MIF method. Results: Eighteen patients with normal cerebrospinal fluid were found. The blood CRP was all negative. 83 cases of IgE cerebrospinal fluid in Ig heavy, very heavy was significantly lower than the light, common type. Cerebrospinal fluid IgM was significantly higher, elevated significantly elevated IgG. Severe B and C cerebrospinal fluid CRP were significantly higher. However, no case of cerebrospinal fluid in 1 case was positive. Conclusion: It is proved that Ig and CRP in the cerebrospinal fluid can be used to diagnose and differentiate CNS infection or as infectious diseases, especially for the identification of JN, CNS and JN. On the type of Japanese JE and various types of JE prognosis of a certain help.