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目的探讨分析压力调节容量控制通气与同步间歇指令通气在老年慢性阻塞性肺疾病合并呼吸衰竭中的临床应用价值。方法 91例老年慢性阻塞性肺疾病合并呼吸衰竭患者,根据住院单双号随机分为对照组(46例)与研究组(45例)。两组患者入院后均给予常规治疗,在此基础上,对照组采取同步间歇指令通气治疗,研究组采取压力调节容量控制通气治疗。比较两组的治疗效果。结果治疗后研究组总有效率为91.1%,显著优于对照组的78.3%(P<0.05);研究组动脉血二氧化碳分压(PaCO_2)及动脉血氧分压(PaO_2)均优于对照组(P<0.05);研究组气道峰压及每分钟通气量均优于对照组(P<0.05);研究组并发症发生率为6.7%,显著低于对照组的17.4%(P<0.05)。结论压力调节容量控制通气治疗老年慢性阻塞性肺疾病并呼吸衰竭可在短时间内改善患者血气指标及呼吸力学指标,进而改善患者临床症状,效果优良。
Objective To investigate the clinical value of pressure-controlled volume controlled ventilation and synchronized intermittent mandatory ventilation in senile chronic obstructive pulmonary disease with respiratory failure. Methods Ninety-one elderly patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into control group (n = 46) and study group (n = 45) according to single and double hospitalization. Two groups of patients were given conventional treatment after admission, on this basis, the control group to take synchronized intermittent instruction ventilation, the study group to take pressure-controlled volume control ventilation. Compare the treatment effect of two groups. Results After treatment, the total effective rate was 91.1% in the study group, which was significantly better than 78.3% in the control group (P <0.05). PaCO_2 and PaO_2 in the study group were better than those in the control group (P <0.05). The peak airway pressure and minute ventilation in study group were better than those in control group (P <0.05). The complication rate in study group was 6.7%, which was significantly lower than that in control group (17.4%, P <0.05) ). Conclusion Pressure-controlled volume-controlled ventilation in elderly patients with chronic obstructive pulmonary disease and respiratory failure can improve the patient’s blood gas and respiratory mechanics indicators in a short period of time, thus improving the clinical symptoms of patients with excellent results.