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目的评价营养支持在妊娠合并急性胰腺炎患者中的应用及其疗效。方法以我科2013年1月至2016年6月期间住院治疗的全部31例妊娠合并急性胰腺炎患者为研究对象,描述营养支持的应用,并比较肠外营养(parenteral nutrition,PN)与肠外营养联合肠内营养(enteral nutrition,EN)应用的临床效果。结果妊娠合并轻症急性胰腺炎患者8例(25.81%)均未进行营养支持,妊娠合并中重症急性胰腺炎患者中,分别有32.26%(10/31)和41.94%(13/31)的患者采用PN、PN和EN联合进行营养支持。PN和EN联合营养支持治疗组的感染发生率(18.18%)、腹胀缓解时间(3.85±1.07)d、体温恢复正常时间(6.31±2.29)d、住院时间以及住院费用均显著低于PN支持治疗组(P<0.05),但不同营养支持方式治疗组间的胎儿终止妊娠率、早产率和足月生产率差异无统计学意义(P>0.05)。结论在妊娠合并急性胰腺炎病例中,营养支持应用广泛;肠外营养与肠内营养联合营养支持总体临床效果优于肠外营养。
Objective To evaluate the application of nutritional support in patients with pregnancy complicated with acute pancreatitis and its curative effect. Methods A total of 31 patients with pregnancy-induced acute pancreatitis admitted to our department between January 2013 and June 2016 were enrolled in this study. The application of nutritional support was described. Parenteral nutrition (PN) and parenteral nutrition Clinical effects of enteral nutrition combined with enteral nutrition. Results No nutritional support was found in 8 cases (25.81%) of pregnancy complicated with mild acute pancreatitis. Among the patients with severe acute pancreatitis complicated with pregnancy, 32.26% (10/31) and 41.94% (13/31) Adopt PN, PN and EN for nutritional support. The incidence of infection (18.18%), abdominal distension time (3.85 ± 1.07) d, normal body temperature recovery time (6.31 ± 2.29) days, hospital stay and hospitalization expenses in PN and EN combined nutritional support group were significantly lower than those in PN supportive therapy group (P <0.05). However, there was no significant difference in the rate of fetal termination, preterm birth and full-term birth rate among different nutritional support groups (P> 0.05). Conclusion In the cases of acute pancreatitis complicated by pregnancy, nutrition support is widely used. The overall clinical effect of parenteral nutrition and enteral nutrition combined nutritional support is better than that of parenteral nutrition.