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BCG膀胱内灌注治疗膀胱癌具有肯定的疗效,已为大家所公认。但随着应用范围的不断扩大,一些较为少见的严重并发症也相继增多。因此,有理由引起我们的警惕与重视。我院自1985年以来,用BCG膀胱内灌注防治膀胱癌36例,有4例发生了严重并发症;其中1例BCG血循播散,2例膀胱大出血(有1例同时合并左侧附睾炎),1例尿道周围BCG肉芽肿。现报告并讨论如下: 病例简介 (例1)男,57岁。于1989年11月,因膀胱癌行膀胱部分切除术。术后一周开始膀胱内灌注BCG,用60mg溶于50ml生理盐水中,经细导尿管注入膀胱。灌注后1小时,患者出现寒颤高热,体温达40.
BCG intravesical instillation of bladder cancer has a positive effect, has been recognized by everyone. However, with the continuous expansion of the scope of application, some of the more rare and serious complications have also increased. Therefore, it is reasonable to arouse our vigilance and attention. In our hospital since 1985, 36 cases of bladder cancer were treated with intravesical instillation of BCG, and 4 cases had serious complications. One case had BCG bleeding and two cases had hemorrhage of the bladder (one case complicated with left epididymitis ), 1 case of urethral BCG granuloma. Now report and discuss as follows: Introduction (case 1) male, 57 years old. In November 1989, a partial bladder resection for bladder cancer. One week after the operation, intravesical instillation of BCG was started, and 60 mg dissolved in 50 ml saline and injected into the bladder through a thin catheter. One hour after perfusion, the patient developed shivering fever, body temperature reached 40.