论文部分内容阅读
目的观察肝母细胞瘤术前化疗后的组织学变化。方法采用软X线拍片、瘤组织浸泡银染方法，比较5例肝母细胞瘤化疗前后的组织学变化。结果化疗后瘤组织发生明显的坏死、纤维化，面积达80％以上。栓塞剂在瘤组织中的分布与瘤组织坏死纤维化的分布及程度无关。结论进展期肝母细胞瘤术前化疗有效。较短时间的肝动脉栓塞化疗可以达到与静脉化疗相近的组织学上的抗肿瘤效果。
Objective To observe the histological changes of hepatoblastoma after preoperative chemotherapy. Methods Soft X-ray film and soaking silver staining were used to compare the histological changes of hepatoblastoma before and after chemotherapy. Results Significant necrosis and fibrosis occurred in the tumor tissue after chemotherapy, with an area of more than 80%. Embolization agent in the distribution of tumor tissue necrosis and tumor tissue distribution and extent of necrosis has nothing to do. Conclusion Preoperative chemotherapy of advanced hepatoblastoma is effective. Shorter course of hepatic arterial chemoembolization can achieve the same histological anti-tumor effect as intravenous chemotherapy.