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本文报告76例小儿重型地中海贫血（地贫）大部脾动脉栓塞（PSE）术后较长期疗效观察。其中55例为β地贫。21例为α地贫，PSE时年龄最小1．5岁，体重最轻7公斤，经过半年～9年的追踪观察结果表明，PSE使患儿巨脾显著缩小，生活能力明显增强。PSE对地贫贫血改善、减少输血有较好疗效，尤其α地贫与部分重型β地贫可长期不需输血。PSE后患儿细胞免疫功能明显增强，抗感染能力提高，明显改善了患儿的体力和生活能力。PSE是当前治疗重型地贫的有效方法。
This article reports 76 patients with pediatric heavy thalassemia (thalassemia) most of the splenic artery embolization (PSE) postoperative long-term efficacy. 55 cases of β thalassemia. 21 cases of α thalassemia, PSE, the youngest 1.5 years old, the lightest weight 7 kg, after six months to 9 years of follow-up observation showed that PSE significantly reduced splenomegaly in children with significantly increased viability. PSE on the improvement of thalassemia anemia, reduce blood transfusion has a good effect, especially in alpha thalassemia and some heavy beta thalassemia long-term without blood transfusion. PSE children with cellular immune function was significantly enhanced anti-infective ability, significantly improved children’s physical and life skills. PSE is currently an effective method of treating severe thalassemia.