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目的:观察复方皂矾丸治疗脑胶质瘤化疗后白细胞减少症的临床疗效。方法:选取化疗后伴白细胞减少的脑胶质瘤患者58例为研究对象,随机分为治疗组和对照组,每组29例;治疗组采用复方皂矾丸治疗,对照组采用鲨肝醇片治疗,10周为1个疗程。观察比较两组白细胞计数的变化和白细胞恢复正常的时间。结果:在治疗后的第4、6、8、10周,治疗组白细胞计数均高于对照组,差异有统计学意义(P<0.05)。治疗组患者白细胞恢复正常时间为(5.09±0.89)周,对照组为(8.83±1.04)周,治疗组短于对照组(P<0.05)。结论:复方皂矾丸治疗脑胶质瘤患者化疗后引起的白细胞减少症有较好的疗效,且见效较快。
Objective: To observe the clinical efficacy of compound Zaofan Pills in the treatment of glioma after leukopenia. Methods: Fifty-eight patients with glioma with leukopenia after chemotherapy were selected as study subjects and randomly divided into treatment group and control group with 29 cases in each group. The treatment group was treated with Compound Zaofan Pills, while the control group was treated with batyl alcohol tablets Treatment, 10 weeks for a course of treatment. Observe and compare the change of white blood cell count and the normal time of leukocyte recovery in both groups. Results: In the 4th, 6th, 8th and 10th weeks after treatment, the white blood cell count of the treatment group was higher than that of the control group, with statistical significance (P <0.05). The leukocyte recovery time was (5.09 ± 0.89) weeks in the treatment group and (8.83 ± 1.04) weeks in the control group, but shorter in the treatment group than in the control group (P <0.05). Conclusion: Compound Zaofan Pill has good curative effect on leucopenia induced by chemotherapy in patients with glioma, and has a quick response.