论文部分内容阅读
目的 探讨糖尿病并发脑卒中的临床特点与相关因素 ,便于卒中防治。方法 住院糖尿病并发脑卒中患者 90例 ,均行颅脑CT检查 ,5例行MRI(1例行MRA)检查。并同时进行空腹血糖、血脂和血液流变学测定。结果 90例根据影像学改变分为腔隙性脑梗死 5 0例 (其中多发性腔梗 36例 ,单发性腔梗 14例 ) ,脑梗死 2 5例 ,脑出血 8例 ,出血性脑梗死 3例 ,椎基底动脉供血不足 4例。病变部位 :基底节区 38例 ,侧脑室周围 2 0例。其余病例分布于额叶、小脑、脑干、丘脑等部位。脑梗死的平均空腹血糖值明显高于腔隙性脑梗死 (P <0 .0 1)。脑梗死的LDL c平均值也明显高于腔隙性脑梗死 (P <0 .0 1)。结论 糖尿病并发脑卒中以腔隙性脑梗死多见 (占 5 5 .6 % ) ,且病灶多发 ,分布广泛。病变好发部位以基底节区为主。高血糖及LDL c增高可能是糖尿病并发脑卒中的重要危险因素。
Objective To investigate the clinical features and related factors of stroke complicating diabetes mellitus and to facilitate the prevention and treatment of stroke. Methods Ninety patients with diabetes and stroke were enrolled. All patients underwent brain CT examination and 5 patients underwent MRI (MRA). Fasting blood glucose, blood lipids and hemorheology were measured at the same time. Results 90 cases were classified into 50 cases of lacunar infarction (including 36 cases of multiple parietal infarcts and 14 cases of solitary parietal infarcts) according to the imaging changes. 25 cases of cerebral infarction, 8 cases of cerebral hemorrhage, 3 cases, vertebrobasilar insufficiency in 4 cases. Lesions: 38 cases of basal ganglia, 20 cases of lateral ventricle. The remaining cases distributed in the frontal lobe, cerebellum, brainstem, thalamus and other parts. The average fasting blood glucose of cerebral infarction was significantly higher than that of lacunar infarction (P <0.01). The mean LDLc of cerebral infarction was also significantly higher than that of lacunar infarction (P <0.01). Conclusions Diabetic cerebral infarction is more common in patients with lacunar infarction (55.6%), with multiple lesions and extensive distribution. Lesions predominant sites of basal ganglia. Hyperglycemia and elevated LDL c may be an important risk factor for stroke complicated by diabetes.