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本文作者表明内皮细胞能分泌一种中性粒细胞趋化因子(NCF),其分子物理化学特征与单核细胞衍生的NCF(IL-8)相似。作者用RNA blot分析法测定NCF基因表达。发现重组的人TNF-α以浓度依赖性和时间依赖性方式促进内皮细胞NCF基因表达。TNF-α、IL-1β′或
The authors show that endothelial cells can secrete a neutrophil chemokines (NCFs) whose molecular physicochemical properties are similar to monocyte-derived NCFs (IL-8). The authors used RNA blot analysis to determine NCF gene expression. Recombinant human TNF-α was found to promote endothelial NCF gene expression in a concentration-dependent and time-dependent manner. TNF-α, IL-1β ’or