临床上常遇到顽固而剧烈咳嗽患者,常规治疗往往疗效不佳,颇为棘手,自1993年8月～1994年6月,笔者参考有关文献,试用颅痛定治疗剧烈咳嗽56例,收到满意效果,现报道如下: 本组56例中,男31例,女25例,年龄1～65岁,病程5天～4个月,其中上呼吸道感染17例,急慢性支气管炎39例,在应用颅痛定治疗前均已接受抗感染及常规镇咳药物治疗4天以上无效。 本组病人均使用颅通定片口服,成人每次30mg,日服2～3次,夜间咳剧者加服30mg,儿童按每日每公斤体重1～2mg,分3次服,合并感染者,适当选用抗生素,停药后复发者,再用有效。 疗效评定及结果:咳嗽停止或基本停止为显效,咳嗽程度明显缓解者为有效,无明显缓解者为无效。56例中,显效37例,其中服药当天显效者13例,2 Clinically often encountered stubborn and severe cough patients, conventional treatment is often ineffective, quite difficult, from August 1993 to June 1994, the author reference to the literature, the trial of craniofacial treatment of severe cough in 56 cases, received Satisfactory results, are reported as follows: The group of 56 patients, 31 males and 25 females, aged 1 to 65 years, duration of 5 days to 4 months, of which 17 cases of upper respiratory tract infection, acute and chronic bronchitis in 39 cases, Application cranialgia given before treatment have been anti-infective and conventional antitussive medication for more than 4 days is invalid. The patients were given craniotome fixed tablets oral administration, adult 30mg, 2 to 3 times a day, evening cough who add clothes to take 30mg, children per kilogram of body weight per day 1 ~ 2mg, 3 times service, with infection , Appropriate use of antibiotics, relapse after stopping, and then effective. Efficacy assessment and results: cough stopped or stopped for the marked effect, significant improvement of cough were effective, no significant relief for those who are ineffective. In 56 cases, 37 cases were markedly effective, of which 13 cases were effective on the day of taking the medicine