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目的:分析冠心病患者合并代谢综合征(MS)的临床特点,探讨其与高敏C反应蛋白(hscrp)的相关性。方法:横断面分析经冠脉造影确诊为冠心病的患者346例,分析不同代谢异常的分布及MS组的发病情况,探讨MS组与非MS组的hscrp的水平及MS的4种代谢异常不同组合与hscrp的关系。结果:346例患者中伴有超重或肥胖者186例(53.8%),伴有高血糖者160例(46.2%),伴有高血压者229例(66.2%),伴有血脂紊乱者74例(21.4%),确诊为MS的患者95例(26.3%);MS发病率随着年龄、病程、病情的增长而增加;冠心病合并MS的患者较非MS患者的hscrp显著升高,而且不同的异常代谢组分的组合,hscrp升高所占的比率均高于hscrp正常所占的比率。结论:提示合并代谢综合征的冠心病患者发生心血管事件的危险性增加,尚需加强他汀类药物及中药的使用。
OBJECTIVE: To analyze the clinical features of metabolic syndrome (MS) in patients with coronary heart disease (CHD) and to explore its relationship with high sensitivity C-reactive protein (hscrp). Methods: A cross-sectional analysis of 346 patients with coronary heart disease diagnosed by coronary angiography was performed. The distribution of different metabolic abnormalities and the incidence of MS were analyzed. The levels of hscrp in MS and non-MS groups and the differences of four metabolic abnormalities Combination and hscrp relationship. RESULTS: Of the 346 patients, 186 (53.8%) with overweight or obesity, 160 (46.2%) with hyperglycemia, 229 (66.2%) with hypertension, and 74 with dyslipidemia (21.4%) and 95 cases (26.3%) were diagnosed as MS. The incidence of MS increased with the increase of age, course of disease and condition. The hscrp of patients with coronary heart disease complicated with MS was significantly higher than that of non-MS patients, The combination of abnormal metabolic components, hscrp increased the proportion of higher than normal hscrp ratio. Conclusion: It is suggested that the risk of cardiovascular events in patients with coronary heart disease complicated with metabolic syndrome is increased, and the use of statins and traditional Chinese medicines should be strengthened.