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目的了解手臂振动及振动负荷试验对中枢神经系统功能的影响。方法对振动性白指患者（白指组）、振动作业工人（接振组）进行振动负荷前后脑干听觉诱发电位的变化，并同对照组进行比较。结果振动负荷前后白指组脑干听觉诱发电位的Ⅰ、Ⅲ、Ⅴ波潜伏期及各峰间期和接振组Ⅰ波潜伏期均较对照组明显延长（Ｐ＜００５，Ｐ＜００１）；白指组脑干听觉诱发电位的Ⅰ、Ⅲ、Ⅴ波、各峰间期及接振组Ⅰ、Ⅴ波潜伏期在振动负荷后较振动负荷前明显缩短（Ｐ＜００５）。结论振动可致脑干听通路受累，并使中枢神经系统对刺激的反应性下降；脑干听觉诱发电位结合振动负荷试验对评价手传振动引起的中枢神经系统损害具有一定意义。
Objective To understand the influence of arm vibration and vibration load test on central nervous system function. Methods The changes of brainstem auditory evoked potentials before and after vibrational loading were measured in patients with vibrational white index finger (white-finger group) and vibration workers (vibration-receiving group), and compared with the control group. Results Compared with the control group, latency of Ⅰ, Ⅲ and Ⅴ waves and latency of each peak and Ⅰ wave of the brainstem auditory evoked potentials were significantly prolonged in white matter group before and after vibration load (P <005, P <001 ). The Ⅰ, Ⅲ and Ⅴ wave of brainstem auditory evoked potentials in white matter group were significantly shorter than those before vibration load (P <005). Conclusions Vibration can lead to brain stem auditory pathway involvement and reduce central nervous system responsiveness to stimuli. Brainstem auditory evoked potentials combined with vibrational stress tests are of significance in evaluating central nervous system damage caused by hand vibration.