甲状腺素约80％与甲状腺素结合球蛋白(TBG)(为α球蛋白)结合,20％与白蛋白和甲状腺素结合前白蛋白结合。近来有报告:患者临床甲状腺情况与血清甲状腺激素浓度不相符合,并有甲状腺素(T_4)或三碘甲状腺原氨酸(T_3)与γ球蛋白的异常结合,患者中大部分甲状腺功能正常。本文报告2例。例1,男性,24岁,甲亢患者,血清 T_4为370nmol/L(正常66～139),于72年应用甲基硫氧嘧啶 About 80% of thyroxine binds to thyroxin-binding globulin (TBG), an alpha globulin, and 20% binds to albumin and thyroxine pre-albumin. Recently there are reports: the clinical thyroid situation and serum thyroid hormone concentrations do not match, and thyroxine (T_4) or triiodothyronine (T_3) and γ-globulin abnormal binding, the majority of patients with normal thyroid function. This article reports 2 cases. Example 1, male, 24 years old, hyperthyroidism patients, serum T_4 was 370nmol / L (normal 66 ~ 139), 72-year application of methylthiouracil