本文报道1例皮肌炎患者,于病程中发生全身性隐球菌病,用咪可那唑治疗成功,这是英国的首例报道。病人15岁,女。于1973年出现左侧腓肠肌疼痛和肿胀,继有发热,胸部和三角肌疼痛。血沉为100mm/小时。血清免疫球蛋白 IgM、α_1和α_2球蛋白,乳酸脱氢酶及肌酸磷酸激酶浓度均升高;肌肉活检显示多发性肌炎但无血管炎,口服强的松龙后好转。1974年 This article reports a case of dermatomyositis patients with systemic cryptococcosis in the course of the course of treatment with miconazole success, this is the first report of the United Kingdom. Patient 15 years old, female. Appeared in 1973 left gastrocnemius pain and swelling, followed by fever, chest and deltoid pain. ESR is 100mm / hour. Serum immunoglobulin IgM, α_1 and α_2 globulin, lactate dehydrogenase and creatine phosphokinase concentrations were elevated; muscle biopsy showed no polyangiitis, vasculitis, oral prednisolone improved. 1974