论文部分内容阅读
目的观察雌二醇凝胶在绝经期取宫内节育器(IUD)中的作用。方法选取该中心2015年5月-2016年8月收治的绝经期取IUD妇女80例,随机分为观察组(40例)和对照组(40例)。对照组妇女手术之前不接受任何药物治疗,观察组妇女手术之前接受雌二醇凝胶治疗,然后对两组妇女的宫颈软化程度、取IUD疼痛程度及取IUD成功情况进行统计分析。结果观察组妇女的宫颈全部软化比例75.0%(30/40)显著高于对照组37.5%(15/40),差异有统计学意义(χ~2=5.02,P<0.05),部分软化、未软化比例17.5%(7/40)、7.5%(3/40)均显著低于对照组32.5%(13/40)、30.0%(12/40),差异有统计学意义(χ~2=7.38、9.35,均P<0.05),取IUD轻度疼痛比例67.5%(27/40)显著高于对照组25.0%(10/40),差异有统计学意义(χ~2=11.14,P<0.05),中度、重度疼痛比例25.0%(10/40)、7.5%(3/40)均显著低于对照组40.0%(16/40)、35.0%(14/40),差异有统计学意义(χ~2=12.38、13.96,均P<0.05),取IUD顺利比例72.5%(29/40)显著高于对照组30.0%(12/40),差异有统计学意义(χ~2=6.63,P<0.05),困难、失败比例27.5%(11/40)、0.0%(0/40)均显著低于对照组32.5%(13/40)、37.5%(15/40),差异有统计学意义(χ~2=14.45、15.21,均P<0.05)。结论雌二醇凝胶在绝经期取IUD中的疗效显著,值得在临床推广。
Objective To observe the effect of estradiol gel on IUD in menopause. Methods Eighty IUD women who were admitted to our center from May 2015 to August 2016 were randomly divided into observation group (40 cases) and control group (40 cases). Women in the control group did not receive any medication until surgery, women in the observation group received estradiol gel treatment prior to surgery, and then analyzed the degree of cervical softening, the degree of IUD pain, and the success of taking IUD in both groups. Results In the observation group, the total cervix softening ratio was 75.0% (30/40) in the observation group and 37.5% (15/40) in the control group. The difference was statistically significant (χ ~ 2 = 5.02, P <0.05) The rates of softening were 17.5% (7/40) and 7.5% (3/40) respectively, which were significantly lower than those in the control group (32.5%, 30.0%, 12/40) (χ ~ 2 = 7.38 , 9.35, all P <0.05). The rate of mild pain in IUD was 67.5% (27/40), which was significantly higher than that in control group (25.0%, 10/40) (χ ~ 2 = 11.14, P <0.05 ). The rates of moderate and severe pain were 25.0% (10/40) and 7.5% (3/40) were significantly lower than those in the control group (40.0%, 35/40, 14/40, respectively) (χ ~ 2 = 12.38, 13.96, all P <0.05). The percentage of successful IUD in 72.5% (29/40) was significantly higher than that in control group (30.0%, 12/40) , P <0.05). The difficulty and failure rates were significantly lower in 27.5% (11/40) and 0.0% (0/40) than those in control group (32.5%, 37.5%, 15/40) Significance (χ ~ 2 = 14.45, 15.21, all P <0.05). Conclusions The effect of estradiol gel in taking IUD during menopause is significant and worthy of clinical promotion.