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目的分析心肌致密化不全(NVM)患者临床特点及预后。方法回顾性分析1999年10月至2002年9月在第四军医大学西京医院就诊的16例NVM患者的临床资料,并进行了临床随访。结果16例患者中,家族集中性发病者7例;有心功能不全表现者6例;存在心律失常者6例;无症状者6例;因胸痛就诊者2例。15例患者接受了随访,平均随访时间(52.06±8.46)个月,随访期间3例死亡,5例因心力衰竭多次入院治疗(包括1例无症状患者及1例因胸痛就诊患者),1例安装永久性起搏器,1例因下壁心肌梗死行冠脉内支架置入术,5例病情稳定,无明显症状。结论NVM总体预后较差,有症状患者预后明显比无症状患者差,早期诊断并进行危险分层至关重要。
Objective To analyze the clinical features and prognosis of patients with myocardial degeneration (NVM). Methods The clinical data of 16 patients with NVM who visited Xijing Hospital of the Fourth Military Medical University from October 1999 to September 2002 were retrospectively analyzed and followed up. Results Among the 16 patients, there were 7 familial onset patients, 6 patients with cardiac insufficiency, 6 patients with arrhythmia, 6 asymptomatic patients and 2 patients with chest pain. Fifteen patients were followed up with an average follow-up of 52.06 ± 8.46 months, 3 died during follow-up, 5 were hospitalized for multiple heart failure (including 1 asymptomatic patient and 1 patient with chest pain), 1 For example, a permanent pacemaker was installed and one patient underwent coronary stenting for inferior myocardial infarction. Five patients were stable and showed no obvious symptoms. Conclusion The overall prognosis of NVM is poor. The prognosis of symptomatic patients is significantly worse than that of asymptomatic patients. Early diagnosis and risk stratification are very important.