论文部分内容阅读
目的 了解轻度胃肠炎伴发的良性婴儿惊厥 (BICE)在华北地区的发病概况。方法 自 1999年 1月至 2 0 0 1年 4月对因急性胃肠炎 (GE)合并无热惊厥的患儿进行临床观察和出院后随访。结果 在观察研究时间内共有 898例GE患儿住院 ,伴无热惊厥者 16例 ,其中男 9例 ,女 7例 ,发病年龄最小 4 5个月 ,最大 2 6个月 ,1～2岁者共 12例。临床GE症状不严重 ,伴无热惊厥呈全身强直阵挛样发作 ,发作间期EEG(12例 )和视频脑电图监测 (4例 )主要改变为 4～ 5Hzθ波活动和正常睡眠EEG背景波 ,无一例有棘 慢波或尖波发放。其它实验室检查包括 :血清电解质、血糖、肝功能检查均正常 ,3例做脑脊液检查、10例做头颅CT检查结果均正常。惊厥发作易控制。出院后随访 14例 (平均间隔 1年 2个月 )未见惊厥复发 ,生长发育如正常儿。结论 轻度GE可以伴有无热惊厥 ,其发生比例约为 1 78% (16/898) ,惊厥形式为全身强直 阵挛样发作 ,易于控制 ,预后良好 ,故可称之为BICE。
Objective To investigate the incidence of benign infantile convulsion (BICE) associated with mild gastroenteritis in North China. Methods From January 1999 to April 2001, the children with acute febrile gastroenteritis (GE) without febrile seizures underwent clinical observation and follow-up after discharge. Results A total of 898 GE children were hospitalized during the study period, 16 with no febrile seizures, including 9 males and 7 females, with a minimum age of 45 months, a maximum of 26 months, and those aged 1-2 years A total of 12 cases. The clinical symptoms of GE were not severe with tocolysis in the absence of febrile seizures. EEG (12 cases) and video EEG monitoring (4 cases) in the interictal episode were mainly altered to 4-5 Hzθ wave activity and normal sleep EEG background wave , No case of spikes slow wave or spike release. Other laboratory tests include: serum electrolytes, blood glucose, liver function tests were normal, 3 cases of cerebrospinal fluid examination, 10 cases of craniocerebral CT examination results were normal. Seizures easy to control seizures. Follow-up after discharge from hospital 14 cases (average interval of 1 year 2 months) no recurrence of convulsions, growth and development, such as normal children. Conclusion mild GE may be associated with febrile seizures, the incidence of about 78% (16/898), convulsions in the form of tonic-type seizures, easy to control, the prognosis is good, it can be called BICE.