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[目的]研究脑心通联合辅酶Q10胶囊治疗皮质下动脉硬化性脑病的临床疗效。[方法] 60例皮质下动脉硬化性脑病患者随机分为两组。治疗组30例,脑心通3粒,3次/日,辅酶Q10胶囊10mg,3次/日;对照组30例,辅酶Q10胶囊10mg,3次/日。两量表(MMSE)及日常生活活动能力量表(ADL)的评定。[结果] 12周后,两组患者MMSE、ADL评分与治疗前比较,差异有统计学意义;两组间比较,治疗组疗效明显优于对照组,无明显不良反应。结论:脑心通联合辅酶Q10胶囊治疗皮质下动脉硬化性脑病安全有效。
[Objective] To study the clinical effect of Naoxintong combined with coenzyme Q10 capsule on subcortical arteriosclerotic encephalopathy. [Methods] Sixty patients with subcortical arteriosclerotic encephalopathy were randomly divided into two groups. 30 cases in the treatment group, 3 blocks of Naoxintong, 3 times / day, coenzyme Q10 capsule 10mg, 3 times / day; control group 30 cases, coenzyme Q10 capsule 10mg, 3 times / day. Assessment of the two scales (MMSE) and activities of daily living scale (ADL). [Results] After 12 weeks, the scores of MMSE and ADL in both groups were statistically different from those before treatment. The curative effect of the two groups was obviously better than that of the control group with no obvious adverse reactions. Conclusion: Naoxintong combined with coenzyme Q10 capsule is safe and effective in the treatment of subcortical arteriosclerotic encephalopathy.