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大肠癌肝转移的治疗较为棘手。即使能够行手术治疗,由于转移灶未能彻底切除,术后复发率仍较高。如果失去手术机会,常规行体外放射治疗、全身化疗效果亦不佳。如何寻找一条新的治疗途径已经摆在医务工作者面前。放射性核素内照射的临床应用,改变了医师对治疗大肠癌肝转移的常规做法。其中125I粒子组织间植入及90Y玻璃微球灌注栓塞已受到医学界的关注和重视,二者在治疗大肠癌肝转移的应用方面有其独特性及互补性,有着广阔的发展前景。
Colorectal cancer is more difficult to treat liver metastases. Even if the surgery can be performed, the recurrence rate is still high because the metastasis can not be completely removed. If you lose the chance of surgery, routine external beam radiotherapy, systemic chemotherapy effect is not good. How to find a new treatment has been placed in front of medical workers. The clinical application of radionuclide internal irradiation has changed physicians’ practice of treating liver metastasis of colorectal cancer. Among them, 125I implantation of interstitial tissues and 90Y glass microspheres perfusion and embolization have drawn the attention and attention of the medical community. Both of them have their uniqueness and complementarity in the treatment of liver metastasis of colorectal cancer and have broad prospects for development.