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目的探讨早期静脉溶栓治疗急性心肌梗死的临床效果。方法将我院收治的60例急性心肌梗死患者随机分为早期静脉溶栓组(≤6h)30例和延迟静脉溶栓(3～12h)30例,两组均给予常规对症治疗+溶栓治疗。比较两组溶栓治疗后的冠状动脉再通率及不良反应发生情况。结果早期溶栓组再通率为90.0%,延期溶栓组再通率为66.7%,早期溶栓组冠状动脉再通率显著高于延迟溶栓组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论早期溶栓治疗急性心肌梗死,是一种安全有效的方法,值得在临床推广。
Objective To investigate the clinical effect of early intravenous thrombolysis in the treatment of acute myocardial infarction. Methods Sixty patients with acute myocardial infarction admitted to our hospital were randomly divided into early thrombolytic group (≤6h) and delayed thrombolysis (30 ~ 30h). All patients were given conventional symptomatic treatment and thrombolytic therapy . The rate of coronary recanalization and incidence of adverse reactions after thrombolytic therapy in both groups were compared. Results The rate of recanalization was 90.0% in early thrombolysis group and 66.7% in delayed thrombolysis group. The rate of coronary recanalization in early thrombolytic group was significantly higher than that in delayed thrombolytic group (P <0.05) . The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion Early thrombolytic therapy of acute myocardial infarction is a safe and effective method, which is worthy of clinical promotion.