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目的了解我院不良反应(ADR)发生的特点和规律,为临床合理用药提供参考。方法对我院2004年3月4日至2012年12月31日收集上报的105例药品不良反应报告进行回顾性分析与评价。结果在105例药品不良反应中,涉及56种药品,抗菌药物、注射剂和静脉给药途径是引起不良反应发生的三大主要因素。ADR涉及的系统/器官以皮肤及附件损害为主。结论加强药品不良反应监测及其相关知识的宣传,降低ADR的发生率,为确保患者用药安全具有重要意义。
Objective To understand the characteristics and rules of adverse drug reaction (ADR) in our hospital and provide references for clinical rational drug use. Methods A retrospective analysis and evaluation of 105 adverse drug reactions reported in our hospital from March 4, 2004 to December 31, 2012 were collected. Results In the 105 cases of adverse drug reactions involving 56 kinds of drugs, antibiotics, injections and intravenous routes of administration are the three major adverse reactions caused by the three major factors. The systems / organs involved in ADR are predominantly skin and accessory lesions. Conclusion To strengthen the monitoring of adverse drug reactions and the related knowledge of publicity, reduce the incidence of ADR, in order to ensure the safety of patients with medication is of great significance.