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1.定义以同位素原子置换化合物中的原子,就象加上一种标记一样,故称为标记化合物。标记时可以使用放射性核也可以使用稳定性核,可以用其中一种核,也可以用几种核,也可以混合使用。例如甲醇的标记化合物有:~(14)CH_3OH、CH_2DOH、CT_3OH、~(13)CD_3OD、~(14)CH_3~(18)OH(其中D为氘,T为氚)。除同位素效应这种特殊情况不能忽略外,标记后的化合物一般可认为其化学性质不发生变化。另一方面,标记的周位素,利用其某种物理性质,可极其灵敏地被检出,含量极微时也能定量测定。放射性标
1. Definition Substitution of atoms in a compound with an isotope atom is like labeling of a compound with the addition of a label. Can be used when tagging radioactive nuclei can also use the stability of the nuclear, you can use one of the nuclear, you can also use several nuclear, can also be mixed use. For example, the labeled compounds of methanol are: (14) CH_3OH, CH_2DOH, CT_3OH, ~ (13) CD_3OD, ~ (14) CH_3 ~ (18) OH where D is deuterium and T is tritium. In addition to the isotope effect of this special case can not be ignored, the marked compound generally can be considered that its chemical properties do not change. On the other hand, the labeled peripherin can be detected extremely sensitively with certain physical properties, and can be quantitatively determined even when the content is extremely small. Radioactive target