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应用放射配体结合分析，测定４０例正常晚期妊娠妇女及４０例妊高征妇女外周血淋巴细胞β_２－肾上腺素能受体（β_２－ＡＲ）结合量，并测定两组妇女分娩的新生儿体重。结果为：１．正常晚期妊娠妇女外周淋巴细胞β_２－ＡＲ结合量明显降低，妊高征妇女β_２－ＡＲ结合量降低更显著；２．妊高征孕妇组的新生儿出生体重明显低于正常妊娠组的新生儿体重；３．孕妇β_２－ＡＲ结合量与新生儿出生体重呈明显正相关，提示好高征与机体β_２－ＡＲ结合量下降有关，β_２－ＡＲ改变影响胎儿生长发育。
Radioligand binding assay was used to measure the binding quantity of β_2-adrenergic receptor (β_2-AR) in peripheral blood lymphocytes of 40 normal pregnant women and 40 pregnant women with PIH. The body weight of newborns . The result is: 1. The amount of β_2-AR binding in peripheral lymphocytes of women with normal late pregnancy was significantly lower, and the decrease of β_2-AR binding rate was more significant in women with PIH.2. Pregnancy-induced hypertension group of newborns birth weight was significantly lower than the weight of newborns in normal pregnancy group; The binding quantity of β_2-AR in pregnant women was positively correlated with the birth weight of newborn, which suggested that the combination of good hyperintense and the decrease of β_2-AR binding rate was related to the change of β_2-AR.