人体内骨骼肌特异性糖原结合的 1型蛋白磷酸酶(PP1G)是胰岛素激活糖原合成酶途径中的主要磷酸酶 ,在调节糖原合成以及葡萄糖的非氧化代谢过程中起关键作用[1] 。其调节亚单位与骨骼肌糖原有高度亲和力。骨骼肌特异糖原靶向调节亚单位 ,由PPP1R3基因编码。研究发现PPP1R3基因Asp The type 1 phosphatase (PP1G) that binds to skeletal muscle-specific glycogen in humans is a major phosphatase in the insulin-activated glycogen synthase pathway and plays a key role in regulating glycogen synthesis and non-oxidative metabolism of glucose [1 ]. Its regulatory subunits and skeletal muscle glycogen has a high affinity. Skeletal muscle-specific glycogen targeting regulatory subunit, encoded by the PPP1R3 gene. The study found that PPP1R3 gene Asp