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目的进一步观察戊型肝炎临床与病原学。方法对１００４例住院的各型病毒性肝炎，用ＥＩＡ法检测甲～戊五型病毒性肝炎血清标志。结果检出抗ＨＥＶ阳性４２例，检出率为４．１８％。低于同期ＨＢＶ和ＨＡＶ感染，居ＨＡＶ～ＨＥＶ五型感染的第三位。并对４２例ＨＥＶ感染者进行了临床及病原学观察，显示以男性青壮年多见。ＨＥＶ与ＨＢＶ、ＨＡＶ双重感染高于单纯ＨＥＶ感染（Ｐ＜０．０５），其中以ＨＢＶ与ＨＥＶ双重感染最多见，占ＨＥＶ感染的７１．４２％。乙肝肝硬变重叠ＨＥＶ感染易出现病情加重，恢复迁延，预后欠佳。结论ＨＡＶ与ＨＥＶ双重感染比单纯ＨＥＶ感染发病年龄下移（Ｐ＜０．０５），但病情无加重。戊型重型肝炎发病率较高。ＨＥＶ多重感染，临床恢复迁延。
Objective To further observe the clinical and etiological of hepatitis E Methods One hundred and four inpatients with various types of viral hepatitis were enrolled in this study. Serum markers of A, E and E viral hepatitis were detected by EIA. Results 42 cases were positive for anti-HEV, the detection rate was 4.18%. Lower than the same period of HBV and HAV infection, ranking HAV ~ HEV type five infection third. And 42 cases of HEV infection were clinical and etiological observation, showed that more common in young men and women. HEV and HBV, HAV double infection was higher than pure HEV infection (P <0.05), with HBV and HEV double infection the most common, accounting for 71.42% of HEV infection. Hepatitis B cirrhosis overlap prone HEV infection exacerbations, recovery and prolongation, poor prognosis. Conclusions The dual infection of HAV and HEV is lower than the age of onset of simple HEV infection (P <0.05), but the condition is not aggravated. The incidence of severe hepatitis E is higher. HEV multiple infections, clinical recovery and prolongation.