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目的:探讨射频消融治疗老年和非老年肝癌患者疗效。方法:选择2009年4月-2011年6月来我院经皮射频消融(PRFA)治疗后的患者68例,其中老年组34例,非老年组34例,两组患者在病情上无显著差异,两组患者肾、肺、心脏等主要器官均无明显损伤,两组各项生理指标无明显差异,P>0.05。用Redionics公司生产的经皮肝穿刺冷循环射频消融术(Cool-tipRF)进行治疗。治疗依据病灶直径采用不同方法治疗,患者在术后如存在肿瘤为完全灭活或随访过程发现复发情况,采取重复射频消融或无水酒精进行治疗。结果:经过治疗1周后效果无明显差异;1、2、3年内两组在复发率、复发时间、生存率、并发症上无明显差异,P>0.05。老年组、非老年组在1、2、3年内生存率分别为88.2%、65.5%、34.0%和80.5%、49.6%、30.0%,虽然老年组的生存率略高于非老年组但无明显差异,P>0.05。结论:老年患者和非老年患者经过治疗后即时效果、复发率、复发时间、并发症、生存率均无明显差异。
Objective: To investigate the efficacy of radiofrequency ablation in the treatment of elderly and non-elderly patients with liver cancer. Methods: From April 2009 to June 2011, 68 patients who came to our hospital after percutaneous radiofrequency ablation (PRFA) were selected, including 34 elderly patients and 34 non-elderly patients. There was no significant difference between the two groups There was no significant difference in the main organs such as kidney, lung and heart between the two groups. There was no significant difference between the two groups in each physiological index (P> 0.05). Redionics percutaneous liver biopsy using cold-cycle radiofrequency ablation (Cool-tipRF) for treatment. Treatment based on lesion diameter using different methods of treatment, patients with postoperative tumor as completely inactivated or follow-up found that the recurrence of the situation, to take repeated radiofrequency ablation or anhydrous alcohol for treatment. Results: After 1 week of treatment, there was no significant difference in the effect. There was no significant difference in the recurrence rate, recurrence time, survival rate and complications between the two groups in one, two and three years (P> 0.05). The survival rates in the elderly and non-elderly groups were 88.2%, 65.5%, 34.0% and 80.5%, 49.6% and 30.0% respectively in 1, 2 and 3 years. Although the survival rate in the elderly group was slightly higher than that in the non-elderly group Difference, P> 0.05. Conclusion: The immediate effect, recurrence rate, recurrence time, complications and survival rate of elderly patients and non-elderly patients have no significant difference after treatment.