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收集了1985~1992年某石油化工厂(简称石化厂)周围四家综合性医院7695例产妇分娩资料,结合区和该厂环境监测站大气监测和暴露估计指标──距离测量结果,分析石化厂大气污染与不良妊娠结局(先天畸形、死胎、出生低体重、早产等)的关系。结果显示:不同半径距离居住产妇不良妊娠结局发生率间的差异有显著性,并有随距离增大而下降的趋势。随机抽取390名正常结局产妇为对照,与325病例比较,经非条件logistic回归模型控制混杂作用和危险性估计,结果表明:距离与四种不良妊娠结局有关,且随距离的增大危险性降低,提示石化厂污染可能是周围妇女不良妊娠结局的危险因素之一。
A total of 7695 cases of maternal delivery in four general hospitals around a petrochemical factory (referred to as petrochemical factory) from 1985 to 1992 were collected. Combining with the district and the atmospheric monitoring and exposure estimation indicators of the plant’s environmental monitoring station──the distance measurement results, Relationship between air pollution and adverse pregnancy outcome (congenital malformation, stillbirth, low birth weight, premature delivery, etc.). The results showed that there was a significant difference in the incidence of adverse pregnancy outcomes among live maternal women with different radii distances, and there was a tendency to decrease with increasing distance. Randomly selected 390 normal outcome maternal as a control, compared with 325 cases, unconditional logistic regression model to control the promiscuous effect and risk estimates, the results showed that: the distance and the outcome of the four adverse pregnancy, and with increasing distance risk reduction , Suggesting that pollution from petrochemical plants may be one of the risk factors for adverse pregnancy outcome among the surrounding women.