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目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者UPPP对其血液流变指标的影响。方法:我院2004年2月～2006年2月确诊为中度或重度的OSAHS患者30例,AHI≤4011例,AHI>4019例,分别在术前及术后检测红细胞比容,全血黏度(高切变率、中切变率、低切变率),红细胞聚集数。结果:术后3～5个月复查红细胞比容以及全血黏度、红细胞聚集指数,较术前均显著降低(均P<0.01)。结论:通过UPPP治疗可以改善OSAHS的血液流变学的异常,降低OSAHS患者发生心脑血管疾病的危险性。
Objective: To investigate the effect of UPPP on the indexes of hemorheology in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: From February 2004 to February 2006 in our hospital, 30 patients with moderate or severe OSAHS were diagnosed. AHI≤4011 patients and AHI> 4019 patients were examined before and after operation respectively. Hematocrit, whole blood viscosity (High shear rate, mid shear rate, low shear rate), erythrocyte aggregation number. Results: The hematocrit and whole blood viscosity, erythrocyte aggregation index were significantly lower than those before operation in 3 ~ 5 months after operation (all P <0.01). Conclusion: The treatment of UPPP can improve the abnormality of hemorheology in OSAHS and reduce the risk of cardiovascular and cerebrovascular diseases in patients with OSAHS.