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代谢性碱中毒的致病原因是复杂的,其治疗也可能比代谢性酸中毒要困难.代谢性碱中毒可以发生于多种临床情况下,如过量的氢离子丧失或重碳酸盐产生增多等.在一组混合的外科病人群中,代谢性碱中毒比代谢性酸中毒更为常见,而且很少为呼吸机制所充分代偿.当pH值7.55或更高时一般被认为是有害的甚至是危险的.而Wilson等发现当pH值7.65—7.70时,即可协同出现80%的死亡率.此文的目的在于报告Dartmouth—Hitchcock医学中心用静脉输入盐酸治疗严重代谢性碱中毒的经验及其临床指征和应用准则.
The causative agent of metabolic alkalosis is complex and its treatment may be more difficult than metabolic acidosis. Metabolic alkalosis can occur in a variety of clinical situations, such as excessive hydrogen ion loss or increased bicarbonate production Etc. Metabolic alkalosis is more common than metabolic acidosis and rarely compensates for respiratory mechanisms in a mixed group of surgical patients, generally considered harmful at pH 7.55 or higher Even dangerous.While, etc. found that when the pH value of 7.65-7.70, 80% of the synergies can be the mortality rate.This paper aims to report the Dartmouth-Hitchcock Medical Center with intravenous hydrochloric acid in the treatment of severe metabolic alkalosis experience And its clinical indications and application guidelines.