目前广泛应用茶碱长期治疗哮喘。长效茶碱制剂的采用,使血浆茶碱浓度长时间内能维持在10～15mg/l,因而在茶碱治疗上提供了改进的可能。然而这种长期治疗临床上的副作用尚须予以评价。本文报告应用茶碱长期治疗导致血浆丙二酰二醛浓度的增加。方法:动态研究组:哮喘息者8例,平均25岁, Theophylline is currently widely used in the treatment of asthma. The use of long-acting theophylline preparations, the plasma concentration of theophylline can be maintained at 10 ~ 15mg / l for a long time, thus providing theophylline treatment may be improved. However, this long-term treatment of clinical side effects still need to be evaluated. This report reports that long-term treatment with theophylline results in an increase in plasma malondialdehyde concentrations. Methods: Dynamic study group: 8 cases of asthma, average 25 years old,