分析工作仪器化、自动化是分析技术发展的一个重要方面,同时推动了自动滴定仪器的发展。G.M.Hiefje等人在1972年研制的“新的直接数字自动滴定仪”,以电脉冲数计量滴定剂体积,用二阶导数法控制终点。J.T.Stock等人在1976年研制的“数字逻辑电路自动电位滴定仪”,以电子时钟计量滴定剂体积,用预置电位法控制终点。T.W.Huntor等人指出, Analytical instrumentation, automation is an important aspect of the development of analytical techniques, while promoting the development of automatic titration instrument. The “new direct digital autotitrator” developed by G.M. Hiefje et al in 1972 measures the volume of titrant by the number of electric pulses and controls the end point by the second derivative method. J.T.Stock and others in 1976 developed the “Digital Logic Automatic Potentiometric titrator” to titrate the volume of titrant with an electronic clock, with the preset potential method to control the endpoint. T.W. Huntor et al.