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49例大肠癌术前在纤维结肠镜下或在术中向癌灶周围注入吸附抗癌药物的微颗粒活性炭MMC-CH40,以被MMc-CH40染黑的淋巴结作为清除术的标记。结果表明:(1)平均每例清除淋巴结数目、第三站淋巴结转移率和转移度,标记组(分别为42.3个,10.2%,2.0%)均高于对照组(分别为26.7个,3.8%,0.7%)。(2)标记组黑染淋巴结数占清除淋巴结总数的59.5%。(3)在淋巴结转移阳性病例中,标记组平均每例清除8.13个,高于对照组的6.37个。说明该方法对提高大肠癌根治术的彻底性,预防癌复发,提高术后生存率有重要意义。
Forty-four patients with colorectal cancer were injected microcapsular activated carbon (MMC-CH40) with anti-cancer drugs around the tumor site under fiber colonoscopy or intraoperatively. The lymph nodes stained with MMc-CH40 were used as markers of debridement. The results showed that: (1) The average number of lymph nodes removed per site, lymph node metastasis rate at the third station, and metastatic degree were higher in the labeling group (42.3, 10.2%, 2.0%, respectively) than in the control group (respectively It is 26.7, 3.8%, 0.7%). (2) The number of lymph nodes in the marker group accounted for 59.5% of the total number of lymph nodes. (3) In the positive cases of lymph node metastasis, the labeling group cleared 8.13 cases per case, which was higher than 6.37 in the control group. This method is of great significance for improving the thoroughness of colorectal cancer radical resection, preventing cancer recurrence, and improving the postoperative survival rate.