论文部分内容阅读
南京老山制药厂移植上海猴头菌菌种,因地制宜,就地取材,改甘蔗渣培养基为山芋渣培养基,试制成治疗胃病新药“宁猴片”,取得了与上海“猴菇菌”片同样效果。经江苏省及南京市有关单位共同协作,进行了菌种鉴定、毒性试验、化学成分分析、临床疗效验证、生产试制等研究工作,已取得成功,于1977年12月10日至11日,在南京老山召开了验证会。到会代表经过认真讨论,仔细审查了有关技术资料,一致同意如下验证结果: 一、该菌种是真菌门担子菌纲多孔菌目齿菌科猴头属猴头菌,学名[Hericium erimaccus(Bull exFr)Pors],与上海的菌种相同。二、急性毒性试验:小白鼠口服浸膏LD_(50)>25克/公斤(即干培养物150克/公斤),未发现药物引起的毒性反应。
Nanjing Laoshan Pharmaceutical Factory Shanghai Hericium species transplanted, according to local conditions, local materials, change bagasse medium for taro culture medium, trial made into the treatment of stomach new drug “Ning monkey tablets” and made with the "Shanghai mushroom The same effect film. After the cooperation of relevant units in Jiangsu Province and Nanjing Municipality, we carried out research work on strain identification, toxicity test, chemical composition analysis, clinical efficacy verification and trial production, and achieved success. From December 10 to December 11, 1977, Nanjing Laoshan held a verification meeting. The delegates meticulously discussed and carefully scrutinized the relevant technical data and unanimously agreed as follows to verify the results: First, the fungus is a fungus Phytoplasma polysaccharide Myceliophthora, Hericium erimaccus (Bull exFr) Pors], the same strain as Shanghai. Second, the acute toxicity test: mice oral administration LD_ (50)> 25 g / kg (ie, dry culture 150 g / kg), did not find the drug-induced toxicity.