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目的:观察米索前列醇置于宫腔内预防剖宫产产后出血的疗效。方法:选择2004年7月～2006年12月有产后出血高危因素并准备剖宫产的孕妇80例,随机分为观察组和对照组各40例。胎儿娩出时均静脉注射缩宫素10U,观察组胎盘娩出后置米索前列醇200μg于宫腔内。比较两组产后2 h及24 h出血量。结果:观察组产后2 h及24 h出血量分别为(939.43±441.02)ml和(1 189.96±428.36)ml,均少于对照组(P<0.01、P<0.001)。观察组24 h出血>1 500 ml 2例,对照组8例,有统计学意义(P<0.05)。结论:米索前列醇置于宫腔内促子宫收缩作用强,能较好预防剖宫产产后出血。
Objective: To observe the effect of misoprostol placed in the uterine cavity to prevent bleeding after cesarean section. Methods: Eighty pregnant women, who were at risk of postpartum hemorrhage from July 2004 to December 2006, were enrolled in this study. They were randomly divided into observation group (40 cases) and control group (40 cases). Intrauterine injection of oxytocin 10U fetus were delivered, the observation group of placenta delivered post-misoprostol 200μg in the uterine cavity. The bleeding volume was compared between 2 h and 24 h postpartum in both groups. Results: The amount of bleeding at 2 hours and 24 hours after delivery in the observation group was (939.43 ± 441.02) ml and (1 189.96 ± 428.36) ml, respectively, less than that in the control group (P <0.01, P <0.001). Observation group bleeding 24 hours> 1 500 ml in 2 cases, control group 8 cases, with statistical significance (P <0.05). Conclusion: Misoprostol placed in the uterine cavity to promote uterine contraction and strong, can better prevent bleeding after cesarean section.