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发现人红白血病细胞株TF-1可在人重组白细胞介素-9(IL-9)刺激下长期生长达5个月,ILL-9可抑制TF-1细胞的DNA片段化,抗GM-CSF抗体可抑制IL-9刺激的TF-1细胞增殖,从而提供了IL-9的一个新生物学效应。
It was found that human erythroleukemia cell line TF-1 can grow for 5 months under the stimulation of human recombinant interleukin-9 (IL-9). ILL-9 can inhibit the DNA fragmentation of TF-1 cells, Antibodies can inhibit IL-9-stimulated proliferation of TF-1 cells, thereby providing a new biological effect of IL-9.