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目的:探讨轮状病毒肠炎并良性婴幼儿惊厥(BICE)的临床特点,以提高对该病的认识,协助临床诊断和治疗。方法:对我院收治的28例轮状病毒肠炎伴无热惊厥的患儿进行临床观察和随访。结果:经补液对症治疗均痊愈出院,28例中有22例出院后通过门诊随访、电话随访,随访时间为2~14个月,平均随访7.5个月,未见惊厥复发,精神运动发育均正常。结论:本组患儿具有以下特点:(1)秋冬季发病,以婴幼儿为主;(2)惊厥前均有轻度轮状病毒肠炎,轻度脱水,但无酸中毒和电解质紊乱;(3)无热惊厥均在发病3天内,早期可反复发作,全身性发作为主;(4)血生化、脑脊液、脑影像学和发作间期脑电图均正常;(5)预后好,不需要长期抗癫痫治疗。
Objective: To investigate the clinical features of rotavirus enteritis and benign infantile convulsions (BICE) in order to improve the understanding of the disease and assist clinical diagnosis and treatment. Methods: 28 cases of rotavirus enteritis with fever-free convulsion in our hospital were observed and followed up. Results: All the patients were discharged after symptomatic rehydration therapy. Of the 28 patients, 22 were discharged from the hospital and were followed up by phone. The follow-up period was from 2 to 14 months. The patients were followed up for an average of 7.5 months. No recurrence of convulsions was found, and their psychomotor development were normal . Conclusion: This group of children has the following characteristics: (1) fall and winter onset, mainly infants and young children; (2) mild rotavirus enteritis before mild convulsions, mild dehydration, but no acidosis and electrolyte imbalance; ( 3) no febrile seizures are within 3 days of onset, early recurrent episodes, generalized seizures; (4) blood biochemistry, cerebrospinal fluid, brain imaging and interictal EEG are normal; (5) the prognosis is good, not Need long-term anti-epileptic treatment.